Next generation sequencing (NGS) library preparation is a crucial step in the NGS workflow. Product evolution in this area has been swift – from original laborious, multi-day protocols requiring reagents from several suppliers, to complete kits optimized for low input, challenging sample types and automation-ready formats. Powerful and continually evolving methods are currently employed by scientists in basic and clinical research settings, such as whole genome DNA, whole transcriptome RNA, methylated DNA, amplicon sequencing and single cell DNA/RNA library preparation in multiple application areas including oncology, human genetic disease and infectious disease research.

As life science suppliers continue to improve products and services in the NGS library preparation market, NGS library preparation experiment kits and reagents represent a significant and important market within the life sciences industry. Percepta Associates launches this new NGS Library Preparation Life Science Dashboard^TM recognizing that professionals in research supply companies need timely, relevant and practical life science market intelligence in this rapidly-evolving space.

Percepta’s 2020 NGS Library Preparation Life Science Dashboard™ is the first in a series that characterizes the dynamic market for products for NGS library preparation  experiments.   This 2020 Dashboard provides a snapshot of the current market landscape, with forward looking projections.

The 2020 NGS Library Preparation Dashboard™ was developed from responses to a 28-question survey completed by 411 scientists located in North America and Europe. This Dashboard reveals key market indicators for the NGS library preparation market as a whole as well as for the following techniques representing market sub-segments:

DNA Library Preparation

• Whole genome/exome DNA library prep
• Targeted DNA library prep (includes target enrichment probes/panels)
• Single cell/low input DNA library prep
• Methylated DNA library prep
• Amplicon Sequencing/16S Library Prep

RNA Library Preparation

• Whole transcriptome RNA library prep
• Targeted RNA library prep (includes target enrichment probes/panels)
• Small RNA/non-coding RNA library prep
• Single cell/low input RNA library prep

Other Library Prep

• ATAC-Seq/ChIP-Seq Library Prep

The following suppliers were surveyed for this report:

• 10X Genomics
• Active Motif
• Agilent Technologies
• BioCat
• Bioline
• Bio-Rad
• Clontech/Takara Bio
• Diagenode
• Epigentek
• Fluidigm
• GenXPro
• Illumina
• Integrated DNA Technologies (IDT)
• Lexogen
• MilliporeSigma/Merck (including EMD, Sigma)
• New England Biolabs
• Nugen
• Nuvogene
• Oxford Nanopore Technologies
• Perkin Elmer
• Qiagen
• Quanta Bio
• Roche/Kapa
• Swift Biosciences
• Thermo Fisher Scientific
• Twist Bioscience
• Zymo Research

5           Executive Summary

8           Dashboard “At A Glance”

11         Market Opportunity Matrix

13         Respondents Qualification

15         Demographics

18         Frequency of Performance: Life Science Techniques

22         Location, Starting Material and Frequency of Performance: NGS Library Preparation

50         Co-Performance: NGS Library Preparation Experiments & Life Science Techniques

53         Use of NGS Instruments and Automation

61         Throughput, Growth Rates, Price & Monthly Spend

71         Market Size

73         Percent of Spend with Suppliers by Segment (Share of Budget)

98         Customer Satisfaction & Interest in Switching

102       Purchase Decision Factors: Product Features

106       Desired Product Changes

118       Appendix I: Supporting Data

131       Appendix II: Percepta Capabilities and Life Science Dashboards™ Available

Available upon request