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Reports

2013 Nucleic Acid Purification Dashboard Series 1 – China -

2013 Nap China
Catalog number: 1302NPC
Publication date: April 2013
Company-wide electronic copy: $3,975

Please enquire about single-user* electronic copy pricing

*single-user pricing is intended for small companies, of 40 or less employees. Please order these copies directly with Percepta Associates.

Introduction

Nucleic acid purification is one of the few basic methods ubiquitous among scientists using molecular biology techniques to investigate processes such as gene expression, genetic diversity, protein function and molecular interactions. The Nucleic Acid Purification Dashboard was developed from responses to a 25-question survey of 449 scientists predominantly located in China. This Dashboard reveals key market indicators for the nucleic acid purification market as a whole as well as for the following 15 sub-segments:

  • Gel Extraction
  • Post-Reaction Cleanup (i.e. PCR, enzyme digestion)
  • Plasmid DNA Miniprep (1-2 ml culture)
  • Plasmid DNA Midiprep (5-50 ml culture)
  • Plasmid DNA Maxiprep (100 ml culture or more)
  • Genomic DNA from cells or tissue
  • Genomic DNA from whole blood
  • Genomic DNA from FFPE tissue
  • DNA Library Preparation for Next Generation Sequencing
  • RNA Library Preparation for Next Generation Sequencing
  • Total RNA from cells or tissue
  • Total RNA from whole blood
  • Total RNA from FFPE tissue
  • mRNA
  • microRNA

Consistent with the previous series of Nucleic Acid Purification Dashboards™ for North America and Europe, Percepta has launched the first in the series of Nucleic Acid Purification Dashboards™ for the Chinese market. This 2013 Dashboard provides a snapshot of the current Chinese nucleic acid purification market landscape, to establish a foundation of data to which future series of Life Science Dashboard can be compared.

Survey Methodology

In January of 2013, Percepta fielded the Nucleic Acid Purification Survey to a panel of Chinese life science researchers. Individuals were invited by e-mail to click through to a webpage at perceptabioanalytix.com where the survey was hosted.  Invitations were delivered on January 20, 2013 and results collected through February 1, 2013. A total of 449 scientists participated in the survey, of which 401 are actively engaged in performing Nucleic Acid Purification.  Results based on the aggregate of collected responses are revealed in this Nucleic Acid Purification Dashboard.

Respondent Demographics

Respondents from different market segments are well represented. 78.1% of the respondents are employed in academic/non-profit organizations, while 21.9% work in an industrial setting.

Respondents from different geographic regions are well presented. 43.9% of respondents are from North China, and 30.9% reside in East China, which are China’s most developed regions with outstanding scientific research, education and high-tech industries.

Junior, mid-level and senior scientists are well represented in the data set, with the most cited job titles being Graduate Students/Medical Students/Student (37.7% of respondents) and Lab Technician/ Research Assistant/Research Associate (17.5%). A wide variety of scientific areas of specialization is also evident, led by Molecular Biology (indicated by 64.3% of respondents as their area of expertise), Biochemistry (56.6%) and Cell Biology (36.9%).

Small (1 to 5 scientists), mid-size (6 to 10 scientists) and large laboratories (>10 scientists) are well represented in the respondent data set.  A total of 12.4% of survey participants work in labs where one to five people perform experiments. 26.4% are employed in labs with six to ten scientists, while the remaining 61.1% of respondents work in labs where greater than 10 individuals work at the bench.

31.4% of respondents indicated that 1 to 5 people in their laboratories perform nucleic acid purification experiments at least a few times each year. An additional 28.7% of survey participants indicated that 6 to 10 individuals perform nucleic acid purification experiments in their laboratories at least a few times per year. 39.9% of respondents work in labs where greater than 10 people perform nucleic acid purification experiments at least a few times each year.

The three most common primary organisms that scientists work with when performing nucleic acid purification are: human (indicated by 31.7% of respondents), bacteria (24.7%) and mouse (15.0%).

Table of Contents

  • 6 Figures and Tables
  • 12 Executive Summary
  • 14 Nucleic Acid Purification Dashboard “At A Glance”
  • 17 Market Opportunity Matrix
  • 19 Qualification and Demographics
  • 24 Frequency of Performance of Life Science Techniques
  • 27 Frequency of Performance of NAP Methods
  • 62 Use of Commercial Reagents and Format Preference
  • 69 Co-Promotion of NAP Methods and Life Science Techniques
  • 74 Throughput/Usage Rates, Market Growth Rates and Stated Price
  • 81 Market Segment Sizes, Total Market Size and Total Market Growth Rate
  • 83 Market Shares by Segment (Share of Mentions)
  • 132 Purchase and Distribution
  • 138 Customer Satisfaction and Interest in Switching Suppliers
  • 143 Important Product Features That Influence Purchasing Decisions
  • 146 Primary and Secondary Downstream Applications
  • 179 Desired Changes to NAP Products
  • 189 Appendix

Figures and Tables

  • 20 Figure 1: Qualification – Frequency of NAP Performance
  • 21  Figure 2: Summary of Demographics
  • 22  Figure 3: Primary and Secondary Species Focus
  • 25  Figure 4: Percent Performing Various Life Science Techniques at Least a Few Times   per Year
  • 29  Figure 5: Percent Performing Various NAP Methods at Least a Few Times per Year
  • 32  Figure 6: Frequency of Performing Gel Extraction
  • 34  Figure 7: Frequency of Performing Post-Reaction Cleanup
  • 36  Figure 8: Frequency of Performing Plasmid DNA Miniprep Purification
  • 38  Figure 9: Frequency of Performing Plasmid DNA Midiprep Purification
  • 40  Figure 10: Frequency of Performing Plasmid DNA Maxiprep Purification
  • 42  Figure 11: Frequency of Performing Genomic DNA Isolation from Cells or Tissue
  • 44  Figure 12: Frequency of Performing Genomic DNA Isolation from Whole Blood
  • 46  Figure 13: Frequency of Performing Genomic DNA Isolation from FFPE Tissue
  • 48  Figure 14: Frequency of Performing DNA Library Preparation for NGS
  • 50  Figure 15: Frequency of Performing RNA Library Preparation for NGS
  • 52  Figure 16: Frequency of Performing Total RNA Isolation from Cells or Tissue
  • 54  Figure 17: Frequency of Performing Total RNA Isolation from Whole Blood
  • 56  Figure 18: Frequency of Performing Total RNA Isolation from FFPE Tissue
  • 58  Figure 19: Frequency of Performing mRNA Isolation
  • 60  Figure 20: Frequency of Performing microRNA Isolation
  • 66  Figure 21: Preference for NAP Reagent Formats
  • 88 Figure 22: Primary Suppliers of Gel Extraction Products
  • 91  Figure 23: Primary Suppliers of Post-Reaction Cleanup Products
  • 94  Figure 24: Primary Suppliers of Plasmid DNA Miniprep Purification Products
  • 97  Figure 25: Primary Suppliers of Plasmid DNA Midiprep Purification Products
  • 100 Figure 26: Primary Suppliers of Plasmid DNA Maxiprep Purification Products
  • 103 Figure 27: Primary Suppliers of Genomic DNA Isolation (from Cells or Tissue) Products
  • 106 Figure 28: Primary Suppliers of Genomic DNA Isolation (from Whole Blood) Products
  • 109 Figure 29: Primary Suppliers of Genomic DNA Isolation (from FFPE Tissue) Products
  • 112  Figure 30: Primary Suppliers of DNA Library Preparation (for NGS) Products
  • 115  Figure 31: Primary Suppliers of RNA Library Preparation (for NGS) Products
  • 117  Figure 32: Primary Suppliers of Total RNA Isolation (from Cells or Tissue) Products
  • 120 Figure 33: Primary Suppliers of Total RNA Isolation (from Whole Blood) Products
  • 123 Figure 34: Primary Suppliers of Total RNA Isolation (from FFPE Tissue) Products
  • 126 Figure 35: Primary Suppliers of mRNA Isolation Products
  • 129 Figure 36: Primary Suppliers of microRNA Isolation Products
  • 134 Figure 37: Primary Purchase Methods
  • 137 Figure 38: Top Sales Agents/Distributors by Share of Mention
  • 140 Figure 39: Percent Satisfaction with Current NAP Product – No Interest in Switching to a Different Supplier
  • 142 Figure 40: Recent History of Switching (Last 6 Months)
  • 145 Figure 41: Most Important Features
  • 149 Figure 42: Primary & Secondary Applications for Purified Gel Extraction Product
  • 151 Figure 43: Primary & Secondary Applications for Purified Post-Reaction Cleanup Product
  • 153 Figure 44: Primary & Secondary Applications for Purified Miniprep Plasmid DNA
  • 155 Figure 45: Primary & Secondary Applications for Purified Midiprep Plasmid DNA
  • 157 Figure 46: Primary & Secondary Applications for Purified Maxiprep Plasmid DNA
  • 159 Figure 47: Primary & Secondary Applications for Purified Genomic DNA from Cells and  Tissue
  • 161 Figure 48: Primary & Secondary Applications for Purified Genomic DNA from Whole   Blood
  • 163 Figure 49: Primary & Secondary Applications for Purified Genomic DNA from FFPE Tissue
  • 165 Figure 50: Primary & Secondary Applications for Purified DNA Library for NGS
  • 167 Figure 51: Primary & Secondary Applications for Purified RNA Library for NGS
  • 169 Figure 52: Primary & Secondary Applications for Purified Total RNA from Cells or Tissue
  • 171 Figure 53: Primary & Secondary Applications for Purified Total RNA from Whole Blood
  • 173 Figure 54: Primary & Secondary Applications for Purified Total RNA from FFPE Tissue
  • 175 Figure 55: Primary & Secondary Applications for Purified mRNA
  • 177 Figure 56: Primary & Secondary Applications for Purified microRNA
  • 180 Figure 57: Desired Changes to NAP Products
  • 26 Table 1: Frequency of Performing Various Life Science Techniques
  • 30 Table 2: Percent Performing Various NAP Methods
  • 31  Table 3: Summary of Frequency of Performing Various NAP Methods
  • 33  Table 4: Frequency of Performing Gel Extraction
  • 35  Table 5: Frequency of Performing Post-Reaction Cleanup
  • 37  Table 6: Frequency of Performing Plasmid DNA Miniprep Purification
  • 39  Table 7: Frequency of Performing Plasmid DNA Midiprep Purification
  • 41  Table 8: Frequency of Performing Plasmid DNA Maxiprep Purification
  • 43  Table 9: Frequency of Performing Genomic DNA Isolation from Cells or Tissue
  • 45  Table 10: Frequency of Performing Genomic DNA Isolation from Whole Blood
  • 47  Table 11: Frequency of Performing Genomic DNA Isolation from FFPE Tissue
  • 49  Table 12: Frequency of Performing DNA Library Preparation for NGS
  • 51  Table 13: Frequency of Performing RNA Library Preparation for NGS
  • 53  Table 14: Frequency of Performing Total RNA Isolation from Cells or Tissue
  • 55  Table 15: Frequency of Performing Total RNA Isolation from Whole Blood
  • 57  Table 16: Frequency of Performing Total RNA Isolation from FFPE Tissue
  • 59  Table 17: Frequency of Performing mRNA Isolation
  • 61  Table 18: Frequency of Performing microRNA Isolation
  • 64  Table 19: Percent Use of Commercial NAP Reagents
  • 65  Table 20: Preference for NAP Reagent Formats (Academia/Non-Profit Vs. Industry)
  • 71  Table 21: Co-Promotion Opportunities (of Life Science Techniques with NAP Methods)
  • 72  Table 22: Co-Promotion Opportunities (of NAP Methods with Life Science Techniques)
  • 73  Table 23: Co-Promotion Opportunities (of NAP Methods)
  • 76  Table 24: Median, Mean and Trim Mean Monthly Throughput
  • 77  Table 25: Median, Mean and Trim Mean Monthly Throughput (Academia/Non- Profit Vs. Industry)
  • 78  Table 26: Numbers of Isolations Performed per Month
  • 79  Table 27: Projected Growth Rates for Various Nucleic Acid Purification Methods
  • 80 Table 28: Median, Mean and Trim Mean Price Per Isolation
  • 82 Table 29: Estimated 2013/2014 Chinese Market Size for NAP Products
  • 85 Table 30: Market Share Leaders (Share of Mentions)
  • 89 Table 31: Primary Suppliers of Gel Extraction Products
  • 92 Table 32: Primary Suppliers of Post-Reaction Cleanup Products
  • 95 Table 33: Primary Suppliers of Plasmid DNA Miniprep Purification Products
  • 98 Table 34: Primary Suppliers of Plasmid DNA Midiprep Purification Products
  • 101 Table 35: Primary Suppliers of Plasmid DNA Maxiprep Purification Products
  • 104 Table 36: Primary Suppliers of Genomic DNA Isolation (from Cells or Tissue) Products
  • 107 Table 37: Primary Suppliers of Genomic DNA Isolation (from Whole Blood) Products
  • 110 Table 38: Primary Suppliers of Genomic DNA Isolation (from FFPE Tissue) Products
  • 113 Table 39: Primary Suppliers of DNA Library Preparation (for NGS) Products
  • 116 Table 40: Primary Suppliers of RNA Library Preparation (for NGS) Products
  • 118 Table 41: Primary Suppliers of Total RNA Isolation (from Cells or Tissue) Products
  • 121 Table 42: Primary Suppliers of Total RNA Isolation (from Whole Blood) Products
  • 124 Table 43: Primary Suppliers of Total RNA Isolation (from FFPE Tissue) Products
  • 127 Table 44: Primary Suppliers of mRNA Isolation Products
  • 130 Table 45: Primary Suppliers of microRNA Isolation Products
  • 141 Table 46: Satisfaction with NAP Product and Reasons for Dissatisfaction
  • 148 Table 47: Summary of Primary Downstream Applications
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