Overview

The growth and propagation of mammalian cells in culture is a routine but critical precursor to the investigation of such fundamental cellular processes as gene expression and protein function and to the development of therapeutics. Cell culture products are widely used not only by scientists working with traditional cell lines but also by researchers engaged in experiments with such emerging model systems as stem cells and engineered cell lines.

This Cell Culture Dashboard was developed based upon the aggregated responses to a 21-question survey completed by 487 scientists actively engaged in mammalian cell culture predominantly located in North America and Europe. This Dashboard reveals key market indicators for the research market for cell culture products as a whole as well as for the following product segments:

• Basal media
• Fetal bovine serum
• Animal sera
• Balanced salt solutions
• Serum free media
• Dry powdered media
• Growth and attachment factors
• Stem cell culture reagents

Percepta’s 2012 Cell Culture Dashboard™, the fourth in a series of reports, examines the characteristics and dynamics of the market for cell culture products. This 2012 Dashboard provides a snapshot of the current market landscape that has been compared with data from the 2010 and 2008 Cell Culture Dashboards, providing an ongoing story of how the market is adapting to new products, new competitors, new cell culture methods, and new sales and marketing strategies.

Survey Methodology

In June of 2012, Percepta fielded the Mammalian Cell Culture Survey to a subset of the company’s panel of more than 60,000 life scientists. Individuals were invited by e-mail blast to click through to a webpage at perceptabioanalytix.com where the survey was hosted. Invitations were delivered on June 20, 2012 and results collected through June 25, 2012. A total of 514 scientists participated in the survey, of which 487 are actively engaged in performing mammalian cell culture and 9 plan to culture mammalian cells in the next 12 months. Results based on the aggregate of collected responses are revealed in this Cell Culture Dashboard.

Important Note: This report only includes analyses related to the research market for cell culture products and not the market for products used in bioproduction or pharmaceutical manufacturing.

Respondent Demographics

Respondents from the academic, government and commercial market segments are well represented. 62.5% of respondents are employed in an academic setting, of which 51.8% of respondents work at universities, colleges, or medical schools, 7.2% are employed at hospitals or medical centers, and 3.5% in private research institutes. 4.9% of respondents work for a government organization. 17.1% of respondents work for biotechnology companies, while 10.7% are employed by pharmaceutical companies. Overall, 31.1% of respondents work in industrial laboratories.

66.1% of respondents are from North America (60.7% in the United States and 5.4% in Canada); while 32.9% reside in Europe.

 

Junior (Lab Tech, Grad Students, Post-Doctoral Fellow), mid-level (Department Manager, Project Manager, Scientist, Core Manager, Professor, Instructor, Lab Manager) and senior (PI, Group Leader, Lab Director, Senior Scientist, CEO) scientists are well represented in the data set, with the most cited job titles being Post-doctoral or Research Fellow (15.8% of respondents) and Scientist (13.0%).

A wide variety of scientific areas of specialization is also evident, led by cell biology (indicated by 23.5% of respondents as their primary area of expertise), biochemistry (12.6%), microbiology / infectious disease / virology (11.1%), immunology (8.6%), and drug discovery (8.2%).

Small (1 to 5 scientists), medium (6 to 10 scientists) and large (>10 scientists) laboratories are well represented. A total of 51.8% of respondents are from laboratories where between 1 and 5 scientists perform cell culture. 25.1% of respondents work in labs where between 6 and 10 people culture mammalian cells, while 20.5% are from labs where more than 10 people perform this technique.

 

Table of Contents

• Figures and Tables
• Executive Summary
• Key Findings and Implications
• Cell Culture Dashboard
• Cell Culture Market Opportunity Matrix
• Survey Methodology
• Survey Invitation Text
• Respondent Demographics
• Frequency of Performance of Life Science Techniques
• Frequency of Cell Culture Product Use
• Throughput/Usage Rates and Market Growth Rates
• Respondents’ Stated Price per Liter for Cell Culture Products
• Total Market Size and Total Market Growth Rate
• Market Share Data (Share of Mention) for Basal Media
• Market Share Data (Share of Mention) for Fetal Bovine Serum
• Market Share Data (Share of Mention) for Other Animal Sera
• Market Share Data (Share of Mention) for Balanced Salt Solutions
• Market Share Data (Share of Mention) for Serum Free Media
• Market Share Data (Share of Mention) for Dry Powdered Media
• Market Share Data (Share of Mention) for Growth and Attachment Factors
• Market Share Data (Share of Mention) for Stem Cell Culture Reagents
• Customer Satisfaction And Interest In Switching Suppliers
• Product Features That Influence Purchasing Decisions
• Primary and Secondary Downstream Applications
• Desired Changes to Cell Culture Products
• Survey Questionnaire

Figures and Tables

• Figure 1: Respondents’ Place of Employment
• Figure 2: Respondents’ Location
• Figure 3: Respondents’ Job Title
• Figure 4: Respondents’ Areas of Expertise/Specialization
• Figure 5: Number of Employees in Respondents’ Laboratories
• Figure 6: Percentage of Respondents Performing Various Life Science Techniques at Least a Few Times Per Year
• Figure 7: Percentage of Respondents Performing Mammalian Cell Culture
• Figure 7A: Change in Percentage of Respondents Performing Mammalian Cell Culture
• Figure 8: Percentage of Respondents Using Various Types of Cell Culture Products in Their Laboratories
• Figure 9: Percentage of Respondents Using Basal Media
• Figure 9A: Change in Percentage of Respondents Using Basal Media
• Figure 10: Percentage of Respondents Using Fetal Bovine Serum
• Figure 10A: Change in Percentage of Respondents Using Fetal Bovine Serum
• Figure 11: Percentage of Respondents Using Other Animal Sera
• Figure 11A: Change in Percentage of Respondents Using Other Animal Sera
• Figure 12: Percentage of Respondents Using Balanced Salt Solutions
• Figure 12A: Change in Percentage of Respondents Using Balanced Salt Solutions
• Figure 13: Percentage of Respondents Using Serum Free Media
• Figure 13A: Change in Percentage of Respondents Using Serum Free Media
• Figure 14: Percentage of Respondents Using Dry Powdered Media
• Figure 14A: Change in Percentage of Respondents Using Dry Powdered Media
• Figure 15: Percentage of Respondents Using Growth and Attachment Factors
• Figure 15A Change in Percentage of Respondents Using Growth and Attachment Factors
• Figure 16: Percentage of Respondents Using Stem Cell Culture Reagents
• Figure 17: Respondents’ Primary Supplier for Basal Media
• Figure 17A: Change in Percentage of Respondents’ Primary Supplier for Basal Media
• Figure 18: Respondents’ Primary Supplier for Fetal Bovine Serum
• Figure 18A: Change in Percentage of Respondents’ Primary Supplier for Fetal Bovine Serum
• Figure 19: Respondents’ Primary Supplier for Other Animal Sera
• Figure 19A: Change in Percentage of Respondents’ Primary Supplier for Other Animal Sera
• Figure 20: Respondents’ Primary Supplier for Balanced Salt Solutions
• Figure 20A: Change in Percentage of Respondents’ Primary Supplier for Balanced Salt Solutions
• Figure 21: Respondents’ Primary Supplier for Serum Free Media
• Figure 21A: Change in Percentage of Respondents’ Primary Supplier for Serum Free Media
• Figure 22: Respondents’ Primary Supplier for Dry Powdered Media
• Figure 22A: Change in Percentage of Respondents’ Primary Supplier for Dry Powdered Media
• Figure 23: Respondents’ Primary Supplier for Growth and Attachment Factors
• Figure 23A: Change in Percentage of Respondents’ Primary Supplier for Growth and Attachment Factors
• Figure 24: Respondents’ Primary Supplier for Stem Cell Culture Reagents
• Figure 25: Percentage of Respondents That Have Switched Suppliers in the Last Six Months
• Figure 26: Most Important Features of Cell Culture Products
• Figure 27: Respondents’ Primary & Secondary Applications for Cultured Mammalian Cells
• Figure 28: Desired Changes to Cell Culture Products

• Table 1: Respondents’ Areas of Expertise/Specialization (Values for Figure 4)
• Table 2: Frequency of Performance of Various Life Science Techniques
• Table 3: Frequency of Co-Performance of Various Life Science Techniques
• Table 4: Frequency of Use for Various Cell Culture Products
• Table 5: Frequency of Co-Performance of Life Science Techniques with the Use of Various Cell Culture Products
• Table 6: Frequency of Use of Cell Culture Products with the Performance of Life Science Techniques
• Table 7: Percentage of Respondents Using Various Numbers of Liters of Product Per Month by Cell Culture Product Type
• Table 8: Change in Percentage of Respondents Using Various Numbers of Liters of Product Per Month in Comparison to 2010 Cell Culture Dashboard
• Table 9: Median, Mean and Trim Mean Monthly Usage Rates for Various Cell Culture Products
• Figure 9A: Median, Mean and Trim Mean Monthly Usage Rates for Various Cell Culture Products (Academia)
• Figure 16: Median, Mean and Trim Mean Monthly Usage Rates for Various Cell Culture Products (Industry)
• Table 10: Projected Growth in the Use of Various Cell Culture Product Categories
• Table 10A: Projected Growth from New Users
• Table 11: Median, Mean and Trim Mean Price Per Liter for Various Cell Culture Products
• Table 12: Estimated 2012/2013 Market Size for Various Cell Culture Products
• Table 13: Respondents’ Primary Supplier for Basal Media by Market Segment
• Table 14: Respondents’ Primary Supplier for Fetal Bovine Serum by Market Segment
• Table 15: Respondents’ Primary Supplier for Other Animal Sera by Market Segment
• Table 16: Respondents’ Primary Supplier for Balanced Salt Solutions by Market Segment
• Table 17: Respondents’ Primary Supplier for Serum Free Media by Market Segment
• Table 18: Respondents’ Primary Supplier for Dry Powdered Media by Market Segment
• Table 19: Respondents’ Primary Supplier for Growth and Attachment Factors by Market Segment
• Table 20: Respondents’ Primary Supplier for Stem Cell Culture Reagents by Market Segment
• Table 21: Market Share Leaders for Cell Culture Products
• Table 22: Percentage of Respondents Satisfied with Various Cell Culture Product Categories and Reasons for Dissatisfaction
• Table 23: Percentage of Respondents Satisfied with Various Cell Culture Product Categories – Comparison to 2010 Cell Culture Dashboard
• Table 24: Most Important Features of Products for Cell Culture – Comparison to 2010 Cell Culture Dashboard
• Table 25: Respondents’ Primary & Secondary Applications for Cultured Mammalian Cells – Comparison to 2010 Cell Culture Dashboard

 

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