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Reports

2009 Nucleic Acid Purification Dashboard Series 2 -

Catalog number: 0906NAP
Publication date: June 2009
Company-wide electronic copy: Complimentary

Please enquire about single-user* electronic copy pricing
* single-user pricing is intended for small companies, of 40 or less employees, to access The Life Science Dashboard. Please order these copies directly with Percepta Associates.

Overview

Overview

Nucleic acid purification is one of the few basic methods ubiquitous among scientists using molecular biology techniques to investigate processes such as gene expression, genetic diversity, protein function and molecular interactions. The Nucleic Acid Purification Dashboard was developed from responses to a 20-question survey of 488 scientists predominantly located in North America and Europe. This Dashboard reveals key market indicators for the nucleic acid purification market as a whole as well as for the following sub-segments:

  • Plasmid minipreps (1-2 ml of culture)
  • Plasmid midipreps (5-50 ml of culture)
  • Large scale plasmid preps/maxipreps (100 ml or more of culture)
  • Genomic DNA purification from cells & tissues and whole blood
  • Total RNA purification from cells & tissues and whole blood
  • mRNA purification
  • microRNA purification

Percepta’s 2009 Nucleic Acid Purification Dashboard™ is a deep dive into the characteristics and dynamics of the market for nucleic acid purification products. This 2009 Dashboard provides a snapshot of the current market landscape that can be compared with data from the 2007 Nucleic Acid Dashboard, providing an ongoing story of how the market is adapting to new products, new competitors, acquisitions and new sales and marketing strategies.

Survey Methodology

In April of 2009, Percepta fielded the Nucleic Acid Purification Survey to a subset of the Percepta BioAnalytix™ Panel of life scientists. Individuals were invited by e-mail blast to click through to a webpage at perceptabioanalytix.com where the survey was hosted. Invitations were delivered beginning on April 2, 2009 and results collected through May 1, 2009. A total of 488 scientists participated in the survey, of which 433 are actively engaged in performing nucleic acid purification and 4 plan to use nucleic acid purification methods in the next 12 months. Results based on the aggregate of collected responses are revealed in this Nucleic Acid Purification Dashboard.

Important Note: This report only includes analyses related to the research market for nucleic acid purification products and not the market for products used in diagnostic assays.

Respondent Demographics

Respondents from the academic, government and commercial market segments are well represented. 52.2% of respondents work at universities/colleges/medical schools; 8.2% are employed at hospitals/medical centers. 13.8% of respondents work for biotechnology companies; 9.4% are employed by pharmaceutical companies. Overall, 25.0% of respondents work in industrial laboratories.

74.8% of respondents are from North America (66.6% in the United States and 8.2% in Canada), while 23.0% reside in Europe.

Junior (Lab Tech, Grad Students), mid level (Post-Doc, Lab Manager) and senior (Professor/PI, Group Leader) scientists are well represented in the data set, with the most cited job titles being Scientist/Senior Scientist (32.0% of respondents) and Professor/Principal Investigator (15.6%).

A wide variety of scientific areas of specialization is also evident, led by Cell Biology and Biochemistry (each indicated by 13.7% of respondents as their primary area of expertise), Genomics (13.0%) and Microbiology/Infectious Disease/ Virology (12.6%).

Small (1-5 scientists), medium (6-20 scientists) and large (>20 scientists) laboratories are well represented. 52.0% of respondents are from laboratories where between 1 and 5 scientists perform nucleic acid purification. 34.8% of respondents work in labs where between 6 and 20 people culture mammalian cells, while the remaining 13.3% are from labs where more than 20 people perform this technique.

Table of contents

Table of Contents

  • 6 Figures and Tables
  • 11 Executive Summary
  • 13 Key Findings and Implications
  • 18 Nucleic Acid Purification Dashboard
  • 23 Nucleic Acid Purification Market Opportunity Matrix
  • 25 Survey Methodology
  • 27 Survey Invitation Text
  • 28 Respondent Demographics
  • 40 Frequency of Performance of Life Science Techniques
  • 45 Frequency of Nucleic Acid Purification Product Use
  • 62 Throughput/Usage Rates and Market Growth Rates
  • 68 Respondent’s Stated Price for Nucleic Acid Purification Products
  • 71 Total Market Size, Market Segment Sizes and Total Market Growth Rate
  • 73 Market Shares by Segment (Share of Mention)
  • 113 Customer Satisfaction And Interest In Switching Suppliers
  • 119 Product Features That Influence Purchasing Decisions
  • 123 Primary and Secondary Downstream Applications
  • 152 Desired Changes to Nucleic Acid Purification Products
  • 162 Survey Questionnaire

List of Figures

  • 30 Figure 1: Respondent’s Place of Employment
  • 32 Figure 2: Respondent’s Country/Region
  • 33 Figure 3: Respondent’s Job Title
  • 35 Figure 4: Respondent’s Areas of Expertise/Specialization
  • 39 Figure 5: Number of Employees in Respondent’s Laboratories
  • 42 Figure 6: Percentage of Respondents Performing Various Life Science Techniques at Least a Few Times per Year
  • 47 Figure 7: Percentage of Respondents Performing Nucleic Acid Purification
  • 48 Figure 8: Percentage of Respondents Using Various Types of Nucleic Acid Purification Products in Their Laboratories
  • 50 Figure 9: Percentage of Respondents Performing Plasmid Miniprep Isolation
  • 51 Figure 10: Percentage of Respondents Performing Plasmid Midiprep Isolation
  • 52 Figure 11: Percentage of Respondents Performing Plasmid Large Scale Isolation
  • 53 Figure 12: Percentage of Respondents Performing Genomic DNA Isolation from Cells or Tissue
  • 54 Figure 13: Percentage of Respondents Performing Genomic DNA Isolation from Whole Blood
  • 55 Figure 14: Percentage of Respondents Performing Total RNA Isolation from Cells or Tissue
  • 56 Figure 15: Percentage of Respondents Performing Total RNA Isolation from Whole Blood
  • 57 Figure 16: Percentage of Respondents Performing mRNA Isolation
  • 58 Figure 17: Percentage of Respondents Performing microRNA Isolation
  • 75 Figure 18: Respondent’s Primary Supplier for Plasmid Miniprep Purification Products
  • 79 Figure 19: Respondent’s Primary Supplier for Plasmid Midiprep Purification Products
  • 83 Figure 20: Respondent’s Primary Supplier for Plasmid Large Scale Plasmid Purification Products
  • 88 Figure 21: Respondent’s Primary Supplier for Purifying Genomic DNA from Cells or Tissue
  • 92 Figure 22: Respondent’s Primary Supplier Purifying Genomic DNA from Whole Blood
  • 97 Figure 23: Respondent’s Primary Supplier for Purifying Total RNA from Cells or Tissue
  • 101 Figure 24: Respondent’s Primary Supplier for Purifying Total RNA from Whole Blood
  • 105 Figure 25: Respondent’s Primary Supplier for Purifying mRNA
  • 109 Figure 26: Respondent’s Primary Supplier for Purifying microRNA
  • 118 Figure 27: Percentage of Respondents That Have Switched Suppliers in the Last Six Months
  • 121 Figure 28: Most Important Features of Nucleic Acid Purification Products
  • 125 Figure 29: Respondent’s Primary Application for Purified Plasmid Miniprep DNA
  • 126 Figure 30: Respondent’s Primary & Secondary Applications for Purified Plasmid Miniprep DNA
  • 127 Figure 31: Respondent’s Primary Application for Purified Plasmid Midiprep DNA
  • 128 Figure 32: Respondent’s Primary & Secondary Applications for Purified Plasmid Midiprep DNA
  • 129 Figure 33: Respondent’s Primary Application for Purified Plasmid Maxiprep DNA
  • 130 Figure 34: Respondent’s Primary & Secondary Applications for Purified Plasmid Maxiprep DNA
  • 133 Figure 35: Respondent’s Primary Application for Genomic DNA Isolated from Cells and Tissue
  • 134 Figure 36: Respondent’s Primary & Secondary Applications for Genomic DNA Isolated from Cells and Tissue
  • 135 Figure 37: Respondent’s Primary Application for Genomic DNA Isolated from Whole Blood
  • 136 Figure 38: Respondent’s Primary & Secondary Applications for Genomic DNA Isolated from Whole Blood
  • 139 Figure 39: Respondent’s Primary Application for Total RNA Isolated from Cells and Tissue
  • 140 Figure 40: Respondent’s Primary & Secondary Applications for Total RNA Isolated from Cells and Tissue
  • 141 Figure 41: Respondent’s Primary Application for Total RNA Isolated from Whole Blood
  • 142 Figure 42: Respondent’s Primary & Secondary Applications for Total RNA Isolated from Whole Blood
  • 145 Figure 43: Respondent’s Primary Application for Purified mRNA
  • 146 Figure 44: Respondent’s Primary & Secondary Applications for Purified mRNA
  • 149 Figure 45: Respondent’s Primary Application for Purified microRNA
  • 150 Figure 46: Respondent’s Primary & Secondary Applications for Purified microRNA

List of Tables

  • 36 Table 1: Respondent’s Areas of Expertise/Specialization Values for Figure 4
  • 43 Table 2: Frequency of Performance of Various Life Science Techniques
  • 44 Table 3: Frequency of Co-Performance of Various Life Science Techniques
  • 49 Table 4: Frequency of Use for Various Nucleic Acid Purification Products
  • 60 Table 5: Frequency of Co-Performance of Life Science Techniques with the Use of Various Nucleic Acid Purification Products
  • 61 Table 6: Frequency of Use of Nucleic Acid Purification Products with the Performance of Life Science Techniques
  • 64 Table 7: Median and Average Monthly Usage Rates for Nucleic Acid Purification Products
  • 65 Table 8: Percentage of Respondents Performing Various Numbers of Purification Reactions per Month by Product Category
  • 67 Table 9: Projected Growth in the Use of Various Nucleic Acid Purification Product Categories
  • 70 Table 10: Median and Average Price Per Prep for Nucleic Acid Purification Products
  • 72 Table 11: Estimated 2009 Global Market Size for Nucleic Acid Purification Products by Category
  • 77 Table 12: Respondent’s Primary Supplier for Plasmid Miniprep Purification Products by Market Segment
  • 81 Table 13: Respondent’s Primary Supplier for Plasmid Midiprep Purification Products by Market Segment
  • 85 Table 14: Respondent’s Primary Supplier for Plasmid Maxiprep Purification Products by Market Segment
  • 86 Table 15: Market Share Leaders for Plasmid Purification Products
  • 90 Table 16: Respondent’s Primary Supplier for Purifying Genomic DNA from Cells or Tissue by Market Segment
  • 94 Table 17: Respondent’s Primary Supplier for Purifying Genomic DNA from Whole Blood by Market Segment
  • 95 Table 18: Market Share Leaders for Genomic DNA Purification Products
  • 99 Table 19: Respondent’s Primary Supplier for Purifying Total RNA from Cells or Tissue by Market Segment
  • 103 Table 20: Respondent’s Primary Supplier for Purifying Total RNA from Whole Blood by Market Segment
  • 107 Table 21: Respondent’s Primary Supplier for Purifying mRNA by Market Segment
  • 111 Table 22: Respondent’s Primary Supplier for Purifying microRNA by Market Segment
  • 112 Table 23: Respondent’s Primary Application for Nucleic Acid Purification Categories – Comparison to 2007 Nucleic Acid Purification Dashboard
  • 115 Table 24: Percentage of Respondents Satisfied with Various Nucleic Acid Purification Product Categories and Reasons for Dissatisfaction
  • 116 Table 25: Percentage of Respondents Satisfied with Nucleic Acid Purification Product Categories – Comparison to 2007 Nucleic Acid Purification Dashboard
  • 122 Table 26: Most Important Features of Products for Nucleic Acid Purification – Comparison to 2007 Nucleic Acid Dashboard
  • 147 Table 27: Respondent’s Primary & Secondary Applications for mRNA – Comparison to 2007 Nucleic Acid Purification Dashboard
  • 151 Table 28: Respondent’s Primary & Secondary Applications for microRNA – Comparison to 2007 Nucleic Acid Purification Dashboard

Questionnaire

Available upon request

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