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Table of Contents
6 Figures and Tables
10 Executive Summary
12 Key Findings and Implications
16 Gene Expression Profiling Dashboard
20 Gene Expression Profiling Market Opportunity Matrix
22 Survey Methodology
24 Survey Invitation Text
25 Respondent Demographics
37 Frequency of Performance of Life Science Techniques
42 Frequency of Performance of Gene Expression Profiling Methods
68 Reaction Throughput and Market Growth Rates
75 Respondent’s Stated Price Per Reaction
78 Total Market Size, Market Segment Sizes and Total Market Growth Rate
80 Market Shares by Segment (Share of Mention)
101 Customer Satisfaction And Interest In Switching Suppliers
109 Product Features That Influence Purchasing Decisions
113 Gene Expression Profiling Applications
147 Desired Changes to Gene Expression Profiling Products
154 Survey Questionnaire
Figures and Tables
27 Figure 1: Respondent's Place of Employment
29 Figure 2: Respondent's Country/Region
31 Figure 3: Respondent's Job Title
33 Figure 4: Respondent's Areas of Expertise/Specialization
36 Figure 5: Number of Employees in Respondent's Laboratories
39 Figure 6: Percentage of Respondents Performing Various Techniques at
Least a Few Times per Year
45 Figure 7: Percentage of Respondents Performing Gene Expression
Profiling Experiments
46 Figure 7A: Change in Percentage of Respondents Performing Gene
Expression Profiling Experiments
47 Figure 8: Percentage of Respondents Performing Various Gene Expression
Profiling Techniques at Least a Few Times per Year
49 Figure 9: Percentage of Respondents That Perform Differential Gene
Expression Studies Using Multiplex PCR
50 Figure 9A: Change in Percentage of Respondents That Perform Differential
Gene Expression Studies Using Multiplex PCR
51 Figure 10: Percentage of Respondents That Perform Digital Gene
Expression Studies/ Molecular Barcodes
52 Figure 11: Percentage of Respondents That Perform Microarray-Based
Gene Expression Studies
53 Figure 11A: Change in Percentage of Respondents That Perform
Microarray-Based Gene Expression Studies
54 Figure 12: Percentage of Respondents That Perform qRT-PCR (cDNA
Template) Using Gene Specific Fluorescent Probes
55 Figure 12A: Change in Percentage of Respondents That Perform qRT-PCR
(cDNA Template) Using Gene Specific Fluorescent Probes
56 Figure 13: Percentage of Respondents That Perform qRT-PCR (cDNA
Template) Using Non-Specific SYBR Green
57 Figure 13A: Change in Percentage of Respondents That Perform qRT-PCR
(cDNA Template) Using Non-Specific SYBR Green
58 Figure 14: Percentage of Respondents That Perform Northern Blot Analysis
59 Figure 14A: Change in Percentage of Respondents That Perform Northern
Blot Analysis
60 Figure 15: Percentage of Respondents That Perform Serial Analysis of
Gene Expression (SAGE) Studies
61 Figure 15A: Change in Percentage of Percentage of Respondents That
Perform Serial Analysis of Gene Expression (SAGE) Studies
62 Figure 16: Percentage of Respondents That Perform Transcriptome
Studies Using Tiling Arrays
63 Figure 17: Percentage of Respondents That Perform Transcriptome
Studies via Short Read Sequencing
84 Figure 18: Respondent's Primary Supplier for Differential Gene Expression
Studies Using Multiplex PCR
86 Figure 19: Respondent's Primary Supplier for Microarray-Based Gene
Expression Studies
88 Figure 19A: Change in Respondent's Primary Supplier for Microarray-Based
Gene Expression Studies
89 Figure 20: Respondent's Primary Supplier for qRT-PCR (cDNA Template)
Using Gene Specific Fluorescent Probes
91 Figure 20A: Change in Respondent's Primary Supplier for qRT-PCR (cDNA
Template) Using Gene Specific Fluorescent Probes
92 Figure 21: Respondent's Primary Supplier for qRT-PCR (cDNA Template)
Using Non-Specific SYBR Green
94 Figure 21A: Change in Respondent's Primary Supplier for qRT-PCR (cDNA
Template) Using Non-Specific SYBR Green
95 Figure 22: Respondent's Primary Supplier for Northern Blot Analysis
97 Figure 23: Respondent's Primary Supplier for Transcriptome Studies via
Short Read Sequencing
103 Figure 24: Respondent Satisfaction with Current Gene Expression
Profiling Methods
107 Figure 25: Percentage of Respondents That Have Switched Suppliers in
the Last Six Months
111 Figure 26: Most Important Features of Products for Gene Expression
Profiling Experiments
117 Figure 27: Respondent's Primary Downstream Application for Differentia
l Gene Expression Studies Using Multiplex PCR
119 Figure 28: Respondent's Primary Downstream Application for
Microarray-Based Gene Expression Studies
121 Figure 29: Respondent's Primary Downstream Application for qRT-PCR
(cDNA Template) Using Gene Specific Fluorescent Probes
123 Figure 30: Respondent's Primary Downstream Application for qRT-PCR
(cDNA Template) Using Non-Specific SYBR Green
125 Figure 31: Respondent's Primary Downstream Application for Northern
Blot Analysis
127 Figure 32: Respondent's Primary Downstream Application for
Transcriptome Studies via Short Read Sequencing
133 Figure 33: Types of Analyses Performed by Respondents for Differential
Gene Expression Studies Using Multiplex PCR
135 Figure 34: Types of Analyses Performed by Respondents for Microarray-
Based Gene Expression Studies
137 Figure 35: Types of Analyses Performed by Respondents for qRT-PCR
(cDNA Template) Using Gene Specific Fluorescent Probes
139 Figure 36: Types of Analyses Performed by Respondents for qRT-PCR
(cDNA Template) Using Non-Specific SYBR Green
141 Figure 37: Types of Analyses Performed by Respondents for Northern
Blot Analysis
143 Figure 38: Types of Analyses Performed by Respondents for
Transcriptome Studies via Short Read Sequencing
34 Table 1: Respondent's Areas of Expertise/Specialization
(Values for Figure 4)
40 Table 2: Frequency of Performance of Various Techniques
41 Table 3: Frequency of Co-Performance of Various Life Science Techniques
48 Table 4: Frequency of Performance of Gene Expression Profiling Methods
65 Table 5: Frequency of Co-Performance of Life Science Techniques with
Gene Expression Profiling Methods
66 Table 6: Frequency of Co-Performance of Gene Expression Profiling
Methods with Life Science Techniques
67 Table 7: Frequency of Co-Performance of Gene Expression Profiling Methods
70 Table 8: Median and Average Monthly Throughput for Gene Expression
Profiling Products
71 Table 9: Percentage of Respondents Processing Various Numbers of
Expression Profiling Samples Per Month
72 Table 10: Highest Throughput Users: Comparison to 2008 Life
Science Dashboard
74 Table 11: Projected Growth in the Performance of Various Gene
Expression Profiling Techniques
77 Table 12: Median and Average Price Per Prep for Gene Expression
Profiling Products
79 Table 13: Estimated Market Size for Gene Expression Profiling Products
99 Table 14: Market Share Leaders for Gene Expression Profiling Products
100 Table 15: Number of Mentions as Primary Supplier for Methods with
Low Numbers of Respondents
104 Table 16: Percentage of Respondents Satisfied with Various Gene
Expression Profiling Products and Reasons for Dissatisfaction
105 Table 17: Respondent's Interest in Switching to a New Supplier for Gene
Expression Profiling Systems: Comparison to 2008 Dashboard
108 Table 18: Previous Suppliers for Respondents That Have Switched Supplier
for Gene Expression Profiling Methods Over the Last Six Months
112 Table 19: Most Important Features of Products for Gene Expression
Profiling Experiments - Comparison to 2007 Gene Expression
Profiling Dashboard
129 Table 20: Respondent’s Primary Application After Various Gene
Expression Profiling Methods
130 Table 21: Number of Mentions of Primary Downstream Applications for
Methods with Low Numbers of Respondents
145 Table 22: Types of Analyses Performed by Respondents Using Various
Gene Expression Profiling Methods
146 Table 23: Number of Mentions of Types of Analyses Performed for
Methods with Low Numbers of Respondents
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