| Table of Contents
6 Figures and Tables
11 Executive Summary
13 Key Findings and Implications
17 Nucleic Acid Separation Dashboard
20 Survey Methodology
22 Survey Invitation Text
23 Respondent Demographics
36 Frequency of Performance of Life Science Techniques
41 Frequency of Performance of Various Nucleic Acid Separation Techniques
58 Reaction Throughput and Market Segment Growth Rates
64 Respondent’s Stated Price Per Reaction
67 Total Market Size, Market Segment Sizes and Total Market Growth Rate
71 Matrix/Method Used to Separate Various Types of Nucleic Acids
84 Market Shares by Segment (Share of Mention)
115 Required Resolution for Nucleic Acid Separation Experiments
128 Required Throughput for Nucleic Acid Separation Experiments
141 Time Required for Nucleic Acid Separation Experiments
154 Customer Satisfaction and Interest in Switching Suppliers
158 Product Features that Influence Purchasing Decisions
162 Desired Changes to Nucleic Acid Separation Products
174 Survey Questionnaire
Figures and Tables
25 Figure 1: Respondent’s Place of Employment
27 Figure 2: Respondent’s Country/Region
29 Figure 3: Respondent’s Position/Job Title
31 Figure 4A: Respondent’s Areas of Expertise/Specialization
32 Figure 4B: Respondent’s Areas of Expertise/Specialization
(Molecular Biology Excluded)
35 Figure 5: Number of Employees in Respondent’s Laboratories
38 Figure 6: Percentage of Respondents Performing Various Life
Science Techniques at Least a Few Times per Year
43 Figure 7: Percentage of Respondents Performing Nucleic Acid Separation
44 Figure 8: Percentage of Respondents Performing Various
Nucleic Acid Separation Methods at Least a Few Times per Year
46 Figure 9: Percentage of Respondents that Analyze Amplified
DNA (Includes AFLP)
47 Figure 10: Percentage of Respondents that Analyze Restriction
Digested DNA (Includes RFLP)
48 Figure 11: Percentage of Respondents that Analyze cRNA or Total RNA Quality
49 Figure 12: Percentage of Respondents that Analyze Small RNA Molecules
50 Figure 13: Percentage of Respondents that Analyze Synthetic DNA or RNA
51 Figure 14: Percentage of Respondents that Perform STR Analysis
52 Figure 15: Percentage of Respondents that Perform HLA Typing Analysis
53 Figure 16: Percentage of Respondents that Perform Pulsed Field Gel
Electrophoresis (Includes Mapping)
54 Figure 17: Percentage of Respondents that Perform Mutation Detection
(Includes SSCP, DGGE)
74 Figure 18: Method/Matrix Used by Respondents that Analyze Amplified
DNA (Includes AFLP)
75 Figure 19: Method/Matrix Used by Respondents that Analyze Restriction
Digested DNA (Includes RFLP)
76 Figure 20: Method/Matrix Used by Respondents that Analyze cRNA or
Total RNA Quality
77 Figure 21: Method/Matrix Used by Respondents that Analyze Small
RNA Molecules
78 Figure 22: Method/Matrix Used by Respondents that Analyze Synthetic
DNA or RNA
79 Figure 23: Method/Matrix Used by Respondents that Perform STR Analysis
80 Figure 24: Method/Matrix Used by Respondents that Perform HLA
Typing Analysis
81 Figure 25: Method/Matrix Used by Respondents that Perform Pulsed Field Gel
Electrophoresis (Includes Mapping)
82 Figure 26: Method/Matrix Used by Respondents that Perform Mutation
Detection (Includes SSCP, DGGE)
88 Figure 27: Respondent's Primary Supplier of Consumables for
Pour-Your-Own Agarose Gels
90 Figure 28: Respondent's Primary Supplier of Instruments Used to
Run Pour-Your-Own Agarose Gels
94 Figure 29: Respondent's Primary Supplier of Precast Agarose Gels
96 Figure 30: Respondent's Primary Supplier of Instruments Used to Run
Precast Agarose Gels
99 Figure 31: Respondent's Primary Supplier of Consumables for Separation
of Nucleic Acids by Capillary Electrophoresis
101 Figure 32: Respondent's Primary Supplier of Capillary Electrophoresis
Instrumentation for Separation of Nucleic Acids
104 Figure 33: Respondent's Primary Supplier of Consumables for
Microfluidics-Based Separation of Nucleic Acids
106 Figure 34: Respondent's Primary Supplier of Instrumentation for
Microfluidics-Based Separation of Nucleic Acids
109 Figure 35: Respondent's Primary Supplier of Consumables Used to
Run Polyacrylamide Gels
111 Figure 36: Respondent's Primary Supplier of Instruments Used to
Run Polyacrylamide Gels
118 Figure 37: Resolution Required by Respondents that Analyze Amplified
DNA (Includes AFLP)
119 Figure 38: Resolution Required by Respondents that Analyze Restriction
Digested DNA (Includes RFLP)
120 Figure 39: Resolution Required by Respondents that Analyze cRNA or
Total RNA Quality
121 Figure 40: Resolution Required by Respondents that Analyze Small
RNA Molecules
122 Figure 41: Resolution Required by Respondents that Analyze Synthetic
DNA or RNA
123 Figure 42: Resolution Required by Respondents that Perform STR Analysis
124 Figure 43: Resolution Required by Respondents that Perform HLA
Typing Analysis
125 Figure 44: Resolution Required by Respondents that Perform Pulsed Field
Gel Electrophoresis (Includes Mapping)
126 Figure 45: Resolution Required by Respondents that Perform Mutation
Detection (Includes SSCP, DGGE)
131 Figure 46: Separation Throughput Required by Respondents that
Analyze Amplified DNA (Includes AFLP)
132 Figure 47: Separation Throughput Required by Respondents that
Analyze Restriction Digested DNA (Includes RFLP)
133 Figure 48: Separation Throughput Required by Respondents that Analyze
cRNA or Total RNA Quality
134 Figure 49: Separation Throughput Required by Respondents that
Analyze Small RNA Molecules
135 Figure 50: Separation Throughput Required by Respondents that
Analyze Synthetic DNA or RNA
136 Figure 51: Separation Throughput Required by Respondents that
Perform STR Analysis
137 Figure 52: Separation Throughput Required by Respondents that Perform
HLA Typing Analysis
138 Figure 53: Separation Throughput Required by Respondents that Perform
Pulsed Field Gel Electrophoresis (Includes Mapping)
139 Figure 54: Separation Throughput Required by Respondents that Perform
Mutation Detection (Includes SSCP, DGGE)
144 Figure 55: Completion Time Required by Respondents that Analyze
Amplified DNA (Includes AFLP)
145 Figure 56: Completion Time Required by Respondents that Analyze
Restriction Digested DNA (Includes RFLP)
146 Figure 57: Completion Time Required by Respondents that Analyze cRNA
or Total RNA Quality
147 Figure 58: Completion Time Required by Respondents that Analyze Small
RNA Molecules
148 Figure 59: Completion Time Required by Respondents that Analyze
Synthetic DNA or RNA
149 Figure 60: Completion Time Required by Respondents that Perform
STR Analysis
150 Figure 61: Completion Time Required by Respondents that Perform HLA
Typing Analysis
151 Figure 62: Completion Time Required by Respondents that Perform Pulsed
Field Gel Electrophoresis (Includes Mapping)
152 Figure 63: Completion Time Required by Respondents that Perform
Mutation Detection (Includes SSCP, DGGE)
157 Figure 64: Percentage of Respondents That Have Switched Suppliers in
the Last Six Months
160 Figure 65: Most Important Features of Products for Nucleic Acid
Separation Experiments
33 Table 1: Respondent's Areas of Expertise/Specialization - Values for
Figures 4A and 4B
39 Table 2: Frequency of Performance of Various Life Science Techniques
40 Table 3: Frequency of Co-Performance of Various Life Science Techniques
45 Table 4: Frequency of Performance of Nucleic Acid Separation Methods
56 Table 5: Frequency of Co-Performance of Life Science Techniques with
Nucleic Acid Separation Methods
57 Table 6: Frequency of Co-Performance of Nucleic Acid Separation
Methods with Life Science Techniques
60 Table 7: Median and Average Monthly Throughput for Nucleic Acid
Separation Techniques
61 Table 8: Percentage of Respondents Separating Various Numbers of Nucleic
Acid Samples (Lanes) Per Month
63 Table 9: Projected Growth in the Performance of Various Nucleic Acid
Separation Techniques
66 Table 10: Median and Average Price Per Sample for Nucleic Acid
Separation Products
69 Table 11: Estimated 2008 Global Market Size for Nucleic Acid Separation
Product Categories
70 Table 12: Estimated 2009 Global Market Size for Nucleic Acid Separation
Product Categories
83 Table 13: Matrix/Method Used to Separate Various Types of Nucleic Acids
89 Table 14: Market Share Leaders for Consumables for Pour-Your-Own
Agarose Gels by Market Segment
91 Table 15: Market Share Leaders for Instruments for Pour-Your-Own
Agarose Gels by Market Segment
95 Table 16: Market Share Leaders for Consumables for Precast Agarose
Gels by Market Segment
97 Table 17: Market Share Leaders for Instruments for Precast Agarose
Gels by Market Segment
100 Table 18: Market Share Leaders for Consumables for Capillary
Electrophoresis by Market Segment
102 Table 19: Market Share Leaders for Instruments for Capillary
Electrophoresis by Market Segment
105 Table 20: Market Share Leaders for Consumables for Microfluidics-Based
Separation of Nucleic Acids by Market Segment
107 Table 21: Market Share Leaders for Instruments for Microfluidics-Based
Separation of Nucleic Acids by Market Segment
110 Table 22: Market Share Leaders for Consumables for Polyacrylamide Gels
by Market Segment
112 Table 23: Market Share Leaders for Instruments for Polyacrylamide Gels
by Market Segment
114 Table 24: Market Share Leaders for Nucleic Acid Separation Products
127 Table 25: Resolution Required for Separation of Various Nucleic Acid
Separation Methods
140 Table 26: Throughput Required for Various Nucleic Acid Separation Methods
153 Table 27: Completion Time Required for Various Nucleic Acid
Separation Methods
156 Table 28: Percentage of Respondents Satisfied with Various
Nucleic Acid Separation Products and Reasons for Dissatisfaction
161 Table 29: Most Important Features of Products for Nucleic Acid
Separation Experiments
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