Table of Contents
5 Figures and Tables
8 Executive Summary
10 Summary of Key Findings
14 Technology and Supplier Review
15 Non Coding RNA Overview
17 miRNA Applications
19 Overview of miRNA Analysis Workflow
21 miRNA Analysis Techniques and Suppliers
35 Supplier Audit and Product Index
36 Leading miRNA Suppliers: North American Market Share Overview
52 Qualitative End-user Assessment of the miRNA Marketplace
53 Survey Methodology and Data Analysis
54 Respondent Demographics
63 Researcher Profile and miRNA Research Practices
64 miRNA Researcher Profile – Primary Sources of Scientific Information
71 miRNA Researcher Profile – Sample Types Analyzed for miRNA Studies
73 miRNA Researcher Profile – Most Useful Methods in Practice
75 miRNA Researcher Profile – Replicates Run Per Assay Type
77 miRNA Researcher Profile – Use of Target Prediction Algorithms
81 Experimental Frequency, Experimental Growth Rate, And Price Per
Reaction of miRNA Analysis Techniques
82 Experimental Frequency of Various miRNA Analysis Techniques
87 Projected Growth Rates for Various miRNA Techniques
90 Respondent’s Stated Price Per Reaction
92 Customer Satisfaction and Interest in Switching Suppliers of miRNA
Analysis Products
93 Current Satisfaction with miRNA Analysis Products and Propensity
for Switching Suppliers
95 Product Features Important to End Users
102 Market Shares by Segment (Share of Mention)
103 Share of Mention of Primary Suppliers of miRNA Products by Segment
115 Estimated Total Market Size and Growth Rate
116 Estimates of North American Market Potential
117 Qualitative End-user Assessment of the miRNA Marketplace
122 Supplier Opportunity Analysis
132 Appendix:
Verbatim User Insight
Survey Solicitation
Survey Questionnaire
List of Figures
16 Figure 1: miRNA Processing
20 Figure 2: miRNA Analysis Flowchart
55 Figure 3: Respondent’s Place of Employment
57 Figure 4: Respondent’s Country/Region
58 Figure 5: Respondent’s Job Title
60 Figure 6: Respondent’s Primary Area of Expertise/Specialization
62 Figure 7: Number of Employees in Respondent’s Laboratory
65 Figure 8: Percent of Respondents that Perform miRNA Experiments
66 Figure 9: Preferred Journal of miRNA Researchers
68 Figure 10: Preferred Web Site of miRNA Researchers
70 Figure 11: Print Versus Online Loyalty Comparison – Nature and Science
72 Figure 12: Current and Future Sample Types for miRNA Analysis
74 Figure 13: miRNA Techniques that Produce the Most Compelling Data
76 Figure 14: Replicate Practices in miRNA Experiments
78 Figure 15: Respondent's Stated Use of miRNA Prediction Algorithms
79 Figure 16: Percent Usage of Top miRNA Prediction Algorithms
84 Figure 17: Percentage of Respondents Performing Various miRNA
Analysis Techniques at Least a Few Times Per Year
98 Figure 18: Most Important Features of miRNA Purification Products
99 Figure 19: Most Important Features of miRNA Microarray Platform
100 Figure 20: Most Important Features of miRNA qRT-PCR Reagents
101 Figure 21: Most Important Features of miRNA Function Analysis Reagents
105 Figure 22: Market Share (Share of Mention as Primary Supplier) for
miRNA Isolation/ Purification Products
106 Figure 23: Market Share (Share of Mention as Primary Supplier) for
miRNA Cloning/Sub-cloning Products
107 Figure 24: Market Share (Share of Mentions as Primary Supplier) for
miRNA Fluorescent Labeling for Microarray
108 Figure 25: Market Share (Share of Mentions as Primary Supplier) for
miRNA Sequencing Product
109 Figure 26: Market Share (Share of Mentions as Primary Supplier) for
miRNA Northern Blot Products
110 Figure 27: Market Share (Share of Mentions as Primary Supplier) for
miRNA Microarray Profiling Products
111 Figure 28: Market Share (Share of Mentions as Primary Supplier) for
miRNA qRT-PCR Products
112 Figure 29: Market Share (Share of Mentions as Primary Supplier) for
miRNA in situ Hybridization Products
113 Figure 30: Market Share (Share of Mentions as Primary Supplier) for
miRNA Over- Expression Products
114 Figure 31: Market Share (Share of Mentions as Primary Supplier) for
miRNA Inhibition (Knockdown) Products
117 Figure 32: Initial Public Funding Levels and Projected Public Funding
Levels for miRNA In US and EU
118 Figure 33: Estimated Industrial Private Fund Expenditures on Consumable
Materials and Reagents For miRNA Discovery and
Preclinical Research
118 Figure 34: Rates of Peer Reviewed Publications in the Area of miRNA or
Non-coding RNA Research
119 Figure 35: Rate of Patent Applications for Technology Relevant to
miRNA since 2002
List of Tables
37 Table 1: miRNA Analysis Market Share Leaders
43 Table 2: miRNA Analysis Product Index
85 Table 3: Frequency of Performance of Common miRNA Techniques
86 Table 4: Number of Experiments Performed Per Month
89 Table 5: miRNA Analysis Techniques Estimated Annual Growth Rates
91 Table 6: Median and Average Price per Reaction for miRNA Analysis Products
94 Table 7: Current Satisfaction and Propensity for Changing Primary Suppliers
121 Table 8: Market Size and Growth Estimates – miRNA North America
128 Table 9: Supplier Opportunities for miRNA Functional Analysis Products
129 Table 10: Supplier Opportunities for miRNA Purification Products
130 Table 11: Supplier Opportunities for miRNA Microarray Products
131 Table 11: Supplier Opportunities for miRNA qRT-PCR Products |
